Dark Spot Correcting Cream (Hydroquinone+Tretinoin)
Dark Spot Correcting Cream (Hydroquinone+Tretinoin)
EvenTone Correcting Cream helps reduce the appearance of dark spots and uneven skin tone using a targeted blend of hydroquinone, tretinoin, azelaic acid, and hydrocortisone.
Correcting
Brightening
Refining
Benefits
Highlights
- Currently Not Available In: (State restrictions may apply – coverage expanding)
- Prescription Dermatology Treatment – Topical application
- Supports the appearance of more even-looking skin tone
- No hidden membership, consultation, or shipping fees
- A licensed healthcare practitioner in your state will review your assessment and determine eligibility
Potential Benefits
Pigmentation Appearance Support
Hydroquinone and azelaic acid are commonly used in dermatology to support the appearance of uneven pigmentation.
Skin Renewal & Turnover Support
Tretinoin is used to support normal skin cell turnover, which may help improve overall skin texture and appearance over time.
Calming & Irritation Support
Hydrocortisone is included to help support skin comfort and reduce visible irritation during treatment.
Tone Uniformity Support
This combination formulation may be used to support a more even-looking complexion when used as directed under medical supervision.
Adjunct to Dermatologic Care Plans
EvenTone Correcting Cream may be incorporated into a broader provider-guided skincare regimen based on individual needs.
Subscription Plan
- Monthly Billing or Every 3 Months
Order Fulfillment
- Doctor review within 48 hours
- Processing can take 2–10 business days (subject to pharmacy partners)
- Once ready, shipping is via 2-day delivery
Disclaimer
This prescription skincare product is provided based on a licensed healthcare provider’s evaluation. These statements and the product have not been evaluated or approved by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease. Compounded or prescription topical formulations are not FDA-approved, and their safety and efficacy have not been independently verified by the FDA. This information is provided for educational purposes only and should not be considered medical advice. Always consult a licensed healthcare provider before starting any new treatment.
Scientific Sources
1. Antioxidant Support
Study: Glutathione neutralizes free radicals and reduces oxidative stress, protecting cellular components and slowing biological aging.
Source: Meister, A., & Anderson, M. E. (1991). Glutathione. Biochemical Pharmacology, 51(5), 443-451. doi:10.1016/0006-2952(91)90156-G
Study: Declining glutathione levels with age increase oxidative damage and impact cellular health.
Source: Lang, C. A., Mills, B. J., Lang, H. L., et al. (2001). Glutathione and aging. Journal of Anti-Aging Medicine, 4(2), 133-144. doi:10.1089/rej.2001.4.133
2. Detoxification
Study: Glutathione supports liver detoxification by neutralizing toxins and heavy metals.
Source: Hayes, J. D., & McLellan, L. I. (1999). Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress. Free Radical Research, 31(4), 273-300. doi:10.1080/10715769900300851
Study: Glutathione protects against environmental toxins, preventing oxidative stress-induced damage.
Source: Valko, M., Rhodes, C. J., Moncol, J., et al. (2006). Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chemico-Biological Interactions, 160(1), 1-40. doi:10.1016/j.cbi.2005.12.009
3. Immune System Optimization
Study: Glutathione enhances white blood cell activity, strengthening immune responses.
Source: Droge, W. (2002). Free radicals in the physiological control of cell function. Physiological Reviews, 82(1), 47-95. doi:10.1152/physrev.00018.2001
Study: Chronic low-grade inflammation (“inflammaging”) is reduced by glutathione.
Source: Franceschi, C., & Campisi, J. (2014). Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases. The Journals of Gerontology: Series A, 69(Suppl 1), S4-S9. doi:10.1093/gerona/glu057
4. Mitochondrial Health
Study: Glutathione protects mitochondria from oxidative stress, ensuring energy production and function.
Source: Mailloux, R. J., McBride, S. L., & Harper, M. E. (2013). Unearthing the secrets of mitochondrial ROS and glutathione in bioenergetics. Trends in Biochemical Sciences, 38(12), 592-602. doi:10.1016/j.tibs.2013.09.001
Study: Mitochondrial dysfunction linked to aging can be mitigated by antioxidant support.
Source: Lopez-Otin, C., Galluzzi, L., Freije, J. M. P., et al. (2013). The hallmarks of aging. Cell, 153(6), 1194-1217. doi:10.1016/j.cell.2013.05.039
5. Skin Health and Anti-Aging
Study: Glutathione improves skin clarity by inhibiting melanin production, reducing hyperpigmentation.
Source: Weschawalit, S., Thongthip, S., Phongpruksa, T., et al. (2017). Glutathione and its antiaging and antimelanogenic effects. Clinical, Cosmetic and Investigational Dermatology, 10, 147-153. doi:10.2147/CCID.S127361
Study: Antioxidants like glutathione preserve collagen, reducing fine lines and wrinkles.
Source: Pullar, J. M., Carr, A. C., & Vissers, M. C. M. (2017). The roles of vitamin C in skin health. Nutrients, 9(8), 866. doi:10.3390/nu9080866
6. Neurological Health
Study: Glutathione protects brain cells from oxidative damage, reducing the risk of neurodegenerative diseases.
Source: Schulz, J. B., Lindenau, J., Seyfried, J., et al. (2000). Glutathione, oxidative stress and neurodegeneration. European Journal of Biochemistry, 267(16), 4904-4911. doi:10.1046/j.1432-1327.2000.01595.x
Study: Oxidative stress in the brain contributes to cognitive decline, mitigated by glutathione.
Source: Butterfield, D. A., & Halliwell, B. (2019). Oxidative stress, mitochondria, and Alzheimer’s disease. Journal of Neurochemistry, 151(2), 135-149.
7. Cardiovascular Health
Study: Glutathione reduces oxidative stress in blood vessels, improving vascular function.
Source: Ballatori, N., Krance, S. M., Notenboom, S., et al. (2009). Glutathione dysregulation and the etiology and progression of human diseases. Biological Chemistry, 390(3), 191-214. doi:10.1515/BC.2009.033
Study: Antioxidant activity helps lower inflammation and cardiovascular disease risk.
Source: Harrison, D., Griendling, K. K., Landmesser, U., et al. (2003). Role of oxidative stress in atherosclerosis. The American Journal of Cardiology, 91(3A), 7A-11A. doi:10.1016/s0002-9149(02)03144-2
8. Cancer Prevention
Study: Glutathione repairs DNA, protects cells from mutations, and reduces cancer risk.
Source: Traverso, N., Ricciarelli, R., Nitti, M., et al. (2013). Role of glutathione in cancer progression and chemoresistance. Oxidative Medicine and Cellular Longevity, 2013, Article ID 972913. doi:10.1155/2013/972913
Study: Antioxidants like glutathione eliminate carcinogens and support cancer prevention.
Source: Lushchak, V. I. (2011). Free radicals, reactive oxygen species, oxidative stress and its classification. Chemico-Biological Interactions, 192(1-2), 70-78. doi:10.1016/j.cbi.2010.07.012
Expand the questions below
Frequently Asked Questions
What is EvenTone Correcting Cream?
EvenTone Correcting Cream is a prescription topical formulation containing hydroquinone, tretinoin, azelaic acid, and hydrocortisone. It is commonly used in dermatologic care to support the appearance of uneven skin tone under medical supervision.
Who may be considered for EvenTone Correcting Cream?
Use is determined by a licensed healthcare provider based on individual skin concerns, medical history, and clinical evaluation. It may be considered for adults seeking prescription-grade skincare for pigmentation-related concerns.
How is EvenTone Correcting Cream applied?
The cream is applied topically to the affected areas as directed by your healthcare provider. Application frequency and duration are individualized.
How is dosing determined?
Strength, application schedule, and treatment duration are determined by the prescribing provider based on skin response and tolerance.
Who should not use this product?
This product may not be appropriate for individuals who are pregnant, breastfeeding, have certain dermatologic conditions, or are sensitive to any of the ingredients. A full medical and skin history review is required prior to prescribing.
Can this be used with other skincare products?
All skincare products, medications, and supplements should be disclosed during intake. A healthcare provider can help determine appropriate combinations.
Should I inform my primary care provider?
Yes. Patients are encouraged to inform their primary care provider of any prescription skincare treatments to support coordinated and safe care.
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